Under the powerful leadership and instruction of the Ministry of Agriculture and Rural Afairs of China and CAAS, the Harbin Veterinary Research Institute promoted the research and development of African swine fever virus vaccine actively, steadily and orderly. Bu Zhigao’s team developed a safe and efective seven-gene deletion attenuated vaccine (HLJ/18-7GD strain). They have successively completed the laboratory quality research of vaccine products, established an efcient production process with controllable quality, and passed the intermediate trial production. In strict accordance with the implementation scheme approved by the Ministry of Agriculture and Rural Afairs of China, the clinical trial has been successfully implemented. The results further proved that the vaccine is safe and efective in the field, which laid a solid foundation for industrialization and application.

The safety and protective efcacy evaluation of ASFV vaccine in biosafety laboratory